Transporters in Drug Discovery and Development Detailed Concepts and Best Practice

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Transporters in Drug Discovery and Development: Detailed Concepts and Best Practice by Yurong Lai
English | 2013 | ISBN: 1907568212 | 780 pages | PDF | 7 MB

Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development.

It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments.

* A comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development
* Balanced coverage of molecular biology aspects and functional outcomes
* State of art knowledge related to transporter-mediated DDI and the clinical relevance in pharmacokinetics, dynamics, and toxicity

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Tags: Concepts, Practice, Detailed, Development, Discovery

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